Information seeking behavioural paths of physicians for diabetes mellitus care: a qualitative comparative analysis of information needs, sources, and barriers

This study addresses diabetes physicians’ information seeking behavioural paths (digital, conventional, interpersonal) which lead to information needs satisfaction and the barriers encountered in this process. The study was based on empirical evidence from a survey of 159 physicians. Theoretical analysis was informed by Wilson’s model of information seeking behaviour. The data were analysed using fuzzy set qualitative comparative analysis method. The method was successful in identifying five behavioural paths leading to physicians’ information needs satisfaction (professional/health coaching) which demonstrate different relationships between information sources (conventional/interpersonal/digital) and information barriers (personal/digital illiteracy) and five behavioural paths that are not leading to satisfaction

CAR-T cell. the long and winding road to solid tumors

Adoptive cell therapy of solid tumors with reprogrammed T cells can be considered the "next generation" of cancer hallmarks. CAR-T cells fail to be as effective as in liquid tumors for the inability to reach and survive in the microenvironment surrounding the neoplastic foci. The intricate net of cross-interactions occurring between tumor components, stromal and immune cells leads to an ineffective anergic status favoring the evasion from the host's defenses. Our goal is hereby to trace the road imposed by solid tumors to CAR-T cells, highlighting pitfalls and strategies to be developed and refined to possibly overcome these hurdles

First-year medical students' information needs and resource selection: responses to a clinical scenario.

The clinical encounter is an increasingly significant component of the first years of the undergraduate medical curriculum. A student's clinical experience has traditionally begun in the third year of the curriculum. Recently, however, a number of medical schools have initiated programs that provide students with clinical experience in each of their four years. Among the initiatives aimed at increasing the number of graduates intending to pursue primary care careers, for example, has been the placement of students in primary care practices at regular intervals beginning in the first year of the curriculum. While the clinical encounter is understood to be a significant educational experience, little is known about the information needs and information seeking behaviors of students in response to clinical problems

Feasibility and marketing studies of health sciences librarianship education programs.

The University of North Carolina at Chapel Hill evaluated five curricular models designed to improve education for health sciences librarianship. Three of the models enhanced existing degree and certificate programs, and two were new programs for working information professionals. Models were developed with input from experts and a Delphi study; the marketability of the models was tested through surveys of potential students and employers; and recommendations were made as a guide to implementation. The results demonstrated a demand for more specialized curricula and for retraining opportunities. Marketing data showed a strong interest from potential students in a specialized master's degree, and mid-career professionals indicated an interest in postmaster's programs that provided the ability to maintain employment. The study pointed to the opportunity for a center of excellence in health sciences information education to enable health sciences librarians to respond to their evolving roles

The Characteristic of Hyperspectral Image of Wheat Seeds during Sprouting

International audienceThe pre-harvest sprouting of wheat have significant influence for its quality and yield, therefore the fast detection of sprouting extent of wheat is very important for breeding and producing. In this study, the hyperspectral images of these seeds were collected by a near infrared hyperspectral imaging system, the wavelength of which was 850-1700 nm after wheat germination experiment at 0h, 12h, 24h, and 48h. The original light intensity of embryo and endosperm were extracted, and were then changed to reflectivity for later analysis. The image and spectral information of wheat with different parts, different varieties and different sprouting extent were compared. The results showed that after 12h sprouting, the reflectivity of embryo was lower than that of endosperm for the same seed, this is mainly due to the water and fat content of embryo was higher than the endosperm portions. For the same varieties of wheat seed at the germination of 12h, 24h and 48h,in the wavelength range of 870-1300 nm, the reflectivity increased with the increase of sprouting time, it was related to the changes of its internal content of fat in the seed germination process. At 1400nm, the reflectivity of sprouted wheat seeds were all lower than that of dry seeds, it was related to the rise of internal water content in the process of seed germination. Due to differences in seed water absorption and sprouting résistance, for different varieties of wheat seeds, its spectral characteristics are also different. The presented indicated that hyperspectral imaging could reflect the characteristics of sprouted wheat seeds, which provide some basis for explore the sprouting index by hyperspectral imaging